Description

1-Bromo-2-(Methylsulfonylmethyl)Benzene is a versatile and high-purity aromatic building block containing both bromo and methylsulfonylmethyl functional groups. This compound is valued for its role as a key intermediate in advanced organic synthesis, enabling the construction of complex molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific aryl-bromide and sulfone functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its structural motifs contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials with tailored properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Fine Chemical Production: Acts as a key intermediate in the multi-step synthesis of complex dyes, pigments, and other high-value fine chemicals.

Basic Information

Product Name	1-Bromo-2-(Methylsulfonylmethyl)Benzene
CAS No.	25195-52-2
Molecular Formula	C9H11BrO2S
Molecular Weight	263.15 g/mol
Synonyms	2-(Bromomethyl)phenyl methyl sulfone; (2-Bromobenzyl) methyl sulfone; 1-Bromo-2-((methylsulfonyl)methyl)benzene; α-Bromo-o-tolyl methyl sulfone; Benzene, 1-bromo-2-[(methylsulfonyl)methyl]-; o-(Bromomethyl)phenyl methyl sulfone; Methyl (2-bromobenzyl) sulfone
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-2-(Methylsulfonylmethyl)Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.