Description

Tetrakis(Methyldiphenylphosphine)Nickel (0) is a highly specialized organometallic complex featuring a zero-valent nickel center coordinated by four methyldiphenylphosphine ligands. This compound matters as a powerful and versatile catalyst, prized for its ability to facilitate challenging cross-coupling and hydrogenation reactions under mild conditions. It is essential for R&D chemists and process engineers in the pharmaceutical, advanced materials, and fine chemical synthesis sectors who require precise catalytic control. The product is supplied under an inert atmosphere to ensure stability and catalytic activity.

Application

• Cross-Coupling Catalysis: A key catalyst for Negishi, Kumada, and Suzuki-Miyaura type cross-coupling reactions to form C-C bonds.
• Hydrogenation & Reduction: Effective for the selective hydrogenation of alkenes, alkynes, and other unsaturated compounds.
• Oligomerization & Polymerization: Used in the catalytic oligomerization of ethylene and other alkenes for specialty polymer production.
• Pharmaceutical Intermediate Synthesis: Enables critical steps in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Manufacturing: Facilitates the production of high-value agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new catalytic transformations in research laboratories.
• Materials Science: Employed in the deposition of nickel-containing thin films and the synthesis of organometallic precursors.

Basic Information

Product Name	Tetrakis(Methyldiphenylphosphine)Nickel (0)
CAS No.	25037-29-0
Molecular Formula	C52H52NiP4
Molecular Weight	863.51 g/mol
Synonyms	Nickel(0) tetrakis(methyldiphenylphosphine); Tetrakis(methyl(diphenyl)phosphine)nickel(0); Ni[P(CH3)(C6H5)2]4; Ni(PMePh2)4; Nickel-tetrakis(methyl-diphenyl-phosphane); Tetrakis(methyldiphenylphosphane)nickel(0); Bis[diphenyl(methyl)phosphine]nickel(0) (dimer notation)
EINECS	Contact for details

Quality Control

Our Tetrakis(Methyldiphenylphosphine)Nickel (0) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including NMR and elemental analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and decomposition. Keep the container in a cool, dry, well-ventilated place away from incompatible materials. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid
Identification (IR)	Conforms to structure
Assay (Ni content)	Min. 6.7%
Purity (NMR)	Min. 98%
Solubility	Soluble in toluene, THF, DCM

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.