Description

2-Cyclobutylideneacetic Acid is a versatile organic acid featuring a cyclobutene ring fused to an acetic acid moiety, making it a valuable synthon in advanced organic synthesis. Its unique strained-ring structure is crucial for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in fine chemical, pharmaceutical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its reactive alkene and carboxylic acid functionalities.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions, Michael additions, and other cycloaddition chemistry to create complex, polycyclic compounds.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing musk analogs and other complex aroma chemicals due to its bicyclic framework.
• Academic & Industrial R&D: A valuable tool for methodological studies in synthetic organic chemistry and catalysis research.

Basic Information

Product Name	2-Cyclobutylideneacetic Acid
CAS No.	25021-04-9
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	2-Cyclobutene-1-acetic Acid; Cyclobut-1-ene-1-acetic Acid; (Cyclobut-1-en-1-yl)acetic Acid; 1-Cyclobutene-1-acetic Acid; 2-Cyclobutenylacetic Acid; Cyclobutylideneacetic Acid; NSC 163022
EINECS	Contact for details

Quality Control

Our 2-Cyclobutylideneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its acidic nature, store separately from strong bases, oxidizing agents, and reactive metals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.