Description

1-Adamantylmalonic Acid is a high-value, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique rigid adamantane core combined with a reactive malonic acid moiety makes it an essential precursor for creating complex molecular architectures with enhanced stability and specific properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and viral infections, leveraging the lipophilic and stable adamantane scaffold.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the adamantane group can impart resistance to metabolic degradation.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of high-performance polymers, resins, and dendrimers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to construct sophisticated ligands for catalysis, taking advantage of its steric bulk and defined geometry.
• Chemical Research & Development: A versatile starting material in academic and industrial R&D for exploring new organic reactions and synthesizing complex natural product analogs.
• Specialty Fine Chemicals: Incorporated into the production of dyes, photoinitiators, and other performance chemicals requiring a stable polycyclic framework.

Basic Information

Item	Detail
Product Name	1-Adamantylmalonic Acid
CAS No.	24779-68-8
Molecular Formula	C₁₅H₂₂O₄
Molecular Weight	266.33 g/mol
Synonyms	Adamantane-1-ylmalonic Acid; 1-Adamantanemalonic Acid; 1-Adamantylpropanedioic Acid; 1-Carboxyadamantane-1-acetic Acid; Tricyclo[3.3.1.1³,⁷]decane-1-ylmalonic Acid; 1-Adamantylmalonic Acid; Adamantylmalonic Acid; 1-(Tricyclo[3.3.1.1³,⁷]dec-1-yl)propanedioic Acid
EINECS	Contact for details

Quality Control

Every batch of 1-Adamantylmalonic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure product integrity and traceability for your regulatory needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting compliance in GMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.