Description

Zinc Chloride Tetrahydrofuran Complex is a versatile organometallic reagent widely used as a Lewis acid catalyst in organic synthesis. This compound is valued for its ability to facilitate a range of critical transformations, including Friedel-Crafts acylations, Diels-Alder reactions, and the formation of carbon-heteroatom bonds. It is an essential material for research laboratories and industrial-scale chemical production, particularly serving the pharmaceutical, agrochemical, and advanced materials sectors where precise catalytic activity is required.

Application

• Lewis Acid Catalyst: Employed in Friedel-Crafts alkylation and acylation reactions for the synthesis of aromatic ketones and intermediates.
• Polymerization Initiator: Used in the ring-opening polymerization (ROP) of cyclic esters and other monomers to produce biodegradable polymers.
• Pharmaceutical Intermediate Synthesis: Facilitates key bond-forming steps in the manufacture of active pharmaceutical ingredients (APIs).
• Cross-Coupling Reactions: Acts as an additive or co-catalyst in various metal-catalyzed cross-coupling methodologies.
• Organic Synthesis Reagent: Utilized in Diels-Alder cycloadditions, aldol condensations, and the activation of epoxides.
• Agrochemical Production: Involved in the synthesis of complex herbicide and pesticide molecules.
• Materials Science Research: Serves as a precursor or catalyst in the development of novel coordination polymers and metal-organic frameworks (MOFs).

Basic Information

Product Name	Zinc Chloride Tetrahydrofuran Complex
CAS No.	24640-76-4
Molecular Formula	C4H8Cl2OZn
Molecular Weight	220.38 g/mol
Synonyms	Zinc chloride THF complex; Zinc dichloride tetrahydrofuran complex; Tetrahydrofuran-zinc chloride complex; ZnCl2.THF; Zinc chloride (1:1) compd. with tetrahydrofuran; Zinc chloride-tetrahydrofuran adduct; Zinc(II) chloride tetrahydrofuran complex
EINECS	Contact for details

Quality Control

Our Zinc Chloride Tetrahydrofuran Complex is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, moisture content, and heavy metal limits. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms
Assay (ZnCl2 basis)	≥ 95.0 %
THF Content	15.0 - 25.0 %
Water Content (KF)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.