Description

[(R)-2-(1-Methylethylidene)Cyclopropyl]Benzene is a chiral, non-racemic organic compound featuring a cyclopropylbenzene core with an isopropylidene substituent, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry and unique structural motif are critical for imparting specific three-dimensional properties to target molecules, which is essential in the development of high-value, optically active products. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty materials sectors for applications in asymmetric synthesis and chiral ligand development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule affects biological activity.
• Chiral Ligand & Catalyst Precursor: Serves as a foundational structure for designing novel chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Material Science Research: Investigated as a monomer or additive for developing polymers with specific optical or mechanical properties due to its rigid, chiral core.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, optically pure aroma chemicals and flavor compounds.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including new cyclopropanation and cross-coupling strategies.

Basic Information

Product Name	[(R)-2-(1-Methylethylidene)Cyclopropyl]Benzene
CAS No.	24524-55-8
Molecular Formula	C12H14
Molecular Weight	158.24 g/mol
Synonyms	(R)-1-Isopropylidene-2-phenylcyclopropane; (R)-α-Methylstyrylcyclopropane; (R)-2-Isopropylidene-1-phenylcyclopropane; (R)-1-Phenyl-2-(propan-2-ylidene)cyclopropane; (R)-2-(Prop-1-en-2-yl)-1-phenylcyclopropane; Benzene, [(1R)-2-(1-methylethylidene)cyclopropyl]-; (R)-Isopropenylphenylcyclopropane
EINECS	Contact for details

Quality Control

Our [(R)-2-(1-Methylethylidene)Cyclopropyl]Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet exacting standards. We provide full traceability and detailed Certificates of Analysis (COA) that include data for chiral purity (HPLC/GC), assay, and specific impurity profiles. Our quality commitment supports compliance with cGMP and ISO guidelines for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.