Description

[1R-(1Alpha,4Beta,6Alpha)]-4-Hydroxy-4,7,7-Trimethylbicyclo[4.1.0]Heptan-3-One is a high-purity, optically active bicyclic ketone derivative. This compound matters as a sophisticated chiral building block and intermediate for synthesizing complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis, fragrance development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Synthesis: Used in the production of advanced, optically active pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Fine Chemical Building Block: Serves as a versatile starting material for synthesizing complex natural product analogs and specialty chemicals.
• Fragrance & Flavor Chemistry: Acts as a precursor for creating unique terpenoid-derived aroma molecules and flavor compounds.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with specific structural properties.

Basic Information

Product Name	[1R-(1Alpha,4Beta,6Alpha)]-4-Hydroxy-4,7,7-Trimethylbicyclo[4.1.0]Heptan-3-One
CAS No.	24348-06-9
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(1R,4R,6R)-4-Hydroxy-4,7,7-trimethylbicyclo[4.1.0]heptan-3-one; (1R,4R,6R)-3-Norcaran-3-one, 4-hydroxy-4,7,7-trimethyl-; 4-Hydroxy-4,7,7-trimethylbicyclo[4.1.0]heptan-3-one, (1R,4R,6R)-; 3-Bicyclo[4.1.0]heptanone, 4-hydroxy-4,7,7-trimethyl-, (1R,4R,6R)-; Optically active Carane derivative; Chiral hydroxy ketone intermediate
EINECS	Contact for details

Quality Control

Our [1R-(1Alpha,4Beta,6Alpha)]-4-Hydroxy-4,7,7-Trimethylbicyclo[4.1.0]Heptan-3-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and optical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.