Description

[R-(E)]-4-(2,6,6-Trimethyl-2-Cyclohexen-1-Yl)-3-Buten-2-One is a high-purity, optically active ketone compound that serves as a critical chiral intermediate and flavor/fragrance ingredient. Its precise stereochemistry and specific molecular structure make it valuable for synthesizing complex molecules where configuration and purity are paramount. This product is essential for manufacturers in the pharmaceutical, flavor, and fragrance industries seeking reliable, high-quality building blocks for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of retinoids, vitamin A analogs, and other biologically active molecules.
• Flavor & Fragrance Ingredient: Used in the creation of sophisticated woody, ambery, and tobacco-like aroma profiles for perfumes and fine fragrances.
• Fine Chemical Synthesis: Serves as a versatile building block in organic chemistry for constructing complex terpenoid and polyene structures.
• Research & Development: Utilized in academic and industrial R&D for studying stereoselective reactions and developing new synthetic methodologies.
• Cosmetic Ingredients: Incorporated into high-end cosmetic formulations for its specific olfactory characteristics.

Basic Information

Product Name	[R-(E)]-4-(2,6,6-Trimethyl-2-Cyclohexen-1-Yl)-3-Buten-2-One
CAS No.	24190-29-2
Molecular Formula	C13H20O
Molecular Weight	192.30 g/mol
Synonyms	(R)-(E)-α-Ionone; (R)-(-)-α-Ionone; (R,E)-4-(2,6,6-Trimethylcyclohex-2-en-1-yl)but-3-en-2-one; (R)-α-Ionone; (6R)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-3-buten-2-one; (R)-(-)-α-Cyclocitrylideneacetone; (R,E)-α-Ionone
EINECS	Contact for details

Quality Control

Our [R-(E)]-4-(2,6,6-Trimethyl-2-Cyclohexen-1-Yl)-3-Buten-2-One is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for optical purity and chemical identity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurities are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to air, light, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Refractive Index	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.