Description

(-)-3,6,6-Trimethylbicyclo[3.1.1]Hept-2-Ene is a high-purity, chiral monoterpene derivative with the CAS number 23978-81-6. This compound serves as a valuable and versatile chiral building block and intermediate in advanced organic synthesis, prized for its defined stereochemistry and bicyclic framework. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is critical for creating active ingredients, fragrances, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry targeting terpene-based scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its bicyclic structure for biological activity.
• Fragrance & Flavor Ingredient: Acts as a precursor for high-value aroma chemicals and flavor compounds due to its terpenoid backbone.
• Fine Chemical Building Block: Employed in asymmetric catalysis and the synthesis of specialty chemicals requiring a specific enantiomeric form.
• Material Science Research: Investigated as a monomer or modifier for creating polymers with unique optical or structural properties.
• Academic & Industrial R&D: Serves as a standard or starting material in organic chemistry research for method development and mechanistic studies.

Basic Information

Product Name	(-)-3,6,6-Trimethylbicyclo[3.1.1]Hept-2-Ene
CAS No.	23978-81-6
Molecular Formula	C10H16
Molecular Weight	136.23 g/mol
Synonyms	(-)-α-Pinene; (1S,5S)-2,6,6-Trimethylbicyclo[3.1.1]hept-2-ene; (1S)-(-)-α-Pinene; L-α-Pinene; (1S,5S)-(-)-α-Pinene; 2-Pinene, (1S,5S)-(-)-; (-)-2-Pinene; (1S)-2,6,6-Trimethylbicyclo[3.1.1]hept-2-ene
EINECS	245-990-1

Quality Control

Our (-)-3,6,6-Trimethylbicyclo[3.1.1]Hept-2-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Refractive Index (n20D)	1.464 - 1.468
Specific Rotation ([α]D20)	-50° to -55° (c=1 in ethanol)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.