Description

1-(3-Bromophenyl)-4,4,4-Trifluorobutane-1,3-Dione is a specialized fluorinated diketone building block featuring a bromophenyl substituent. This compound is valued for its unique reactivity profile, serving as a versatile synthon in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of β-diketonate ligands for metal-organic frameworks (MOFs) and catalysis.
• Chemical Biology Probes: Useful for creating fluorescent tags or molecular probes due to its reactive diketone and halogenated aromatic structure.
• Organic Synthesis: Acts as a versatile substrate for condensation reactions, cyclizations, and as a precursor to heterocyclic compounds like pyrazoles and isoxazoles.

Basic Information

Item	Details
Product Name	1-(3-Bromophenyl)-4,4,4-Trifluorobutane-1,3-Dione
CAS No.	23975-64-6
Molecular Formula	C10H6BrF3O2
Molecular Weight	295.06 g/mol
Synonyms	3'-Bromo-4,4,4-trifluoro-1-phenylbutane-1,3-dione; 3-Bromophenyl Trifluoroacetylacetone; 1-(3-Bromophenyl)-4,4,4-trifluoro-1,3-butanedione; 3-Bromo-ω,ω,ω-trifluoroacetophenone; 3'-Bromo-ω,ω,ω-trifluoroacetophenone; 3-Bromophenyl 1,1,1-Trifluoro-2,4-butanedione; 3-Bromo-α-(trifluoroacetyl)acetophenone
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)-4,4,4-Trifluorobutane-1,3-Dione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We adhere to relevant industry standards to support our clients' research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.