Description

7-Fluorophthalazin-1(2H)-One is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical agents and agrochemicals, where the fluorine atom and phthalazinone core impart desirable biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fluorinated heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse libraries of compounds for screening.
• Material Science: Potential application in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and process chemistry optimization in academic and CRO/CMO settings.

Basic Information

Product Name	7-Fluorophthalazin-1(2H)-One
CAS No.	23928-52-1
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	7-Fluorophthalazin-1(2H)-one; 7-Fluoro-1(2H)-phthalazinone; 7-Fluoro-2H-phthalazin-1-one; 7-Fluorophthalazinone; 1(2H)-Phthalazinone, 7-fluoro-; 7-Fluoro-1,2-dihydrophthalazin-1-one; 7-Fluorophthalazin-1-ol; 7-Fluoro-1-hydroxyphthalazine
EINECS	Contact for details

Quality Control

Our 7-Fluorophthalazin-1(2H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.