Description

1(2H)-Phthalazinone, 5-Fluoro- is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a key intermediate for the development of novel pharmaceutical compounds and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the phthalazinone scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated phthalazinone structure.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic systems in medicinal and process chemistry.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with unique electronic properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1(2H)-Phthalazinone, 5-Fluoro-
CAS No.	23928-50-9
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	5-Fluoro-1(2H)-phthalazinone; 5-Fluorophthalazin-1(2H)-one; 5-Fluoro-2H-phthalazin-1-one; 5-Fluoro-1-phthalazinone; 5-Fluoro-1,2-dihydrophthalazin-1-one; 5-Fluorophthalazinone; 5-Fluoro-1-oxo-1,2-dihydrophthalazine
EINECS	Contact for details

Quality Control

Our 1(2H)-Phthalazinone, 5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.