Description

3-Hydroxy-3-Phenyl-Cyclobutanecarboxylic Acid is a specialized cyclobutane derivative that serves as a valuable chiral building block and synthetic intermediate in advanced organic synthesis. Its unique fused ring structure containing both hydroxyl and carboxylic acid functional groups makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates and bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective reactions to create enantiomerically pure compounds.
• Ligand and Catalyst Development: Serves as a precursor for novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Investigated as a monomer or building block for novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry development within organic chemistry laboratories.

Basic Information

Product Name	3-Hydroxy-3-Phenyl-Cyclobutanecarboxylic Acid
CAS No.	23761-26-4
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	3-Phenyl-3-hydroxycyclobutanecarboxylic acid; 3-Hydroxy-3-phenylcyclobutane-1-carboxylic acid; 3-Phenylcyclobutane-1-carboxylic acid, 3-hydroxy-; 3-Hydroxy-3-phenyl-1-cyclobutanecarboxylic acid; β-Hydroxy-β-phenylcyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-3-Phenyl-Cyclobutanecarboxylic Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and chiral purity analysis to ensure identity, potency, and chemical purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.