Description

n-Isopropylmethanesulfonamide is a specialized organosulfur compound featuring an isopropyl-substituted sulfonamide functional group. This chemical serves as a versatile and valuable building block and intermediate in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the sulfonamide moiety contributes to biological activity and stability.
• Chemical Research & Development: Employed as a versatile reagent for constructing complex molecular architectures in medicinal chemistry and material science projects.
• Ligand and Catalyst Precursor: Acts as a precursor for specialized ligands in transition metal catalysis or as a component in organocatalysts.
• Polymer Modification: Can be used to introduce sulfonamide functional groups into polymers to alter their physical properties, such as solubility or thermal stability.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	n-Isopropylmethanesulfonamide
CAS No.	23705-43-3
Molecular Formula	C4H11NO2S
Molecular Weight	137.20 g/mol
Synonyms	N-Isopropylmethanesulfonamide; Methanesulfonamide, N-(1-methylethyl)-; 1-Methylethylmethanesulfonamide; Isopropylmethanesulfonamide; N-(Propan-2-yl)methanesulfonamide; 2-Propanamine, N-(methylsulfonyl)-; Isopropyl methanesulfonamide
EINECS	Contact for details

Quality Control

Our n-Isopropylmethanesulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and other relevant techniques. Our quality commitment supports applications requiring high-purity intermediates for GMP (Good Manufacturing Practice) and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.