Description

n-(α,α,α-Trifluoro-m-Tolyl)Benzamidine is a high-purity benzamidine derivative characterized by its trifluoromethyl-substituted aromatic ring. This compound serves as a valuable specialized chemical intermediate and pharmacological research tool, particularly in the development of enzyme inhibitors and active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams, fine chemical manufacturers, and academic research institutions focused on medicinal chemistry and organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly serine protease inhibitors.
• Biochemical Research: Used as a reference standard or inhibitor in enzymatic studies and proteomics research.
• Agrochemical Synthesis: Intermediate for developing advanced crop protection agents and herbicides.
• Material Science: Precursor for specialty polymers and advanced organic materials incorporating fluorine.
• Organic Synthesis: Versatile reagent for constructing complex heterocyclic compounds and amidine-containing molecules.

Basic Information

Product Name	n-(α,α,α-Trifluoro-m-Tolyl)Benzamidine
CAS No.	23557-76-8
Molecular Formula	C14H11F3N2
Molecular Weight	264.25 g/mol
Synonyms	N-[3-(Trifluoromethyl)phenyl]benzenecarboximidamide; Benzamidine, N-[3-(trifluoromethyl)phenyl]-; 3-Trifluoromethylphenylbenzamidine; N-(3-Trifluoromethylphenyl)benzamidine; α,α,α-Trifluoro-m-tolylbenzamidine; m-Trifluoromethylphenylbenzamidine; 23557-76-8; NSC 163063
EINECS	Contact for details

Quality Control

Our n-(α,α,α-Trifluoro-m-Tolyl)Benzamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.