Description

(S)-3,4-Dihydro-3-(4-Hydroxy-2,3,6-Trimethoxyphenyl)-2H-1-Benzopyran-7-Ol CAS NO 23531-99-9 is a high-purity, optically active chroman derivative, a key chiral building block in advanced organic synthesis. This compound is valued for its specific stereochemistry and functionalized aromatic structure, which are critical for developing compounds with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles of new chemical entities.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Fine Chemical Production: Incorporated into the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic Research: Utilized in university and institutional labs for studying chroman chemistry, natural product synthesis, and novel reaction methodologies.

Basic Information

Product Name	(S)-3,4-Dihydro-3-(4-Hydroxy-2,3,6-Trimethoxyphenyl)-2H-1-Benzopyran-7-Ol
CAS No.	23531-99-9
Molecular Formula	C18H20O6
Molecular Weight	332.35 g/mol
Synonyms	(S)-7-Hydroxy-3-(4-hydroxy-2,3,6-trimethoxyphenyl)chroman; (S)-3,4-Dihydro-3-(4-hydroxy-2,3,6-trimethoxyphenyl)-2H-1-benzopyran-7-ol; (S)-Chromanol derivative; (S)-2,3,6-Trimethoxy-4-(7-hydroxy-3,4-dihydro-2H-chromen-3-yl)phenol; (S)-HPMCP derivative; (-)-3,4-Dihydro-3-(4-hydroxy-2,3,6-trimethoxyphenyl)-2H-1-benzopyran-7-ol; (S)-enantiomer of chroman-7-ol derivative
EINECS	Contact for details

Quality Control

Our (S)-3,4-Dihydro-3-(4-Hydroxy-2,3,6-Trimethoxyphenyl)-2H-1-Benzopyran-7-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep the container tightly sealed in a dry environment to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.