Description

4-Pentenoic Acid, Trimethylsilyl Ester is a versatile organosilicon-protected carboxylic acid derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its dual functionality, where the silyl ester acts as a protective group for the carboxylic acid moiety, while the terminal alkene provides a reactive handle for further chemical transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, enabling the synthesis of complex molecules through controlled, multi-step reaction sequences.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers with tailored properties.
• Cross-Coupling Reactions: The alkene functionality participates in Heck, metathesis, and hydrofunctionalization reactions.
• Carboxylic Acid Protection Strategy: The trimethylsilyl ester provides a stable, yet readily cleavable, protecting group for sensitive synthetic routes.
• Fragrance & Flavor Chemistry: Intermediate for the synthesis of specific aroma chemicals and flavor compounds.
• Ligand & Catalyst Development: Used in the preparation of novel chelating ligands and organometallic catalysts.

Basic Information

Product Name	4-Pentenoic Acid, Trimethylsilyl Ester
CAS No.	23523-56-0
Molecular Formula	C8H16O2Si
Molecular Weight	172.30 g/mol
Synonyms	4-Pentenoic Acid TMS Ester; Trimethylsilyl 4-Pentenoate; 4-Pentenoic Acid Trimethylsilyl Ester; Pent-4-enoic Acid Trimethylsilyl Ester; (Trimethylsilyl) 4-pentenoate; TMS 4-Pentenoate; 4-Penten-1-oic Acid, Trimethylsilyl Ester; 23523-56-0
EINECS	Contact for details

Quality Control

Our production of 4-Pentenoic Acid, Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We employ advanced analytical techniques including GC, GC-MS, NMR, and IR spectroscopy for comprehensive identity and purity verification. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.