Description

Tetrahydropiperine is a synthetic derivative of piperine, the primary bioactive compound found in black pepper. This compound is valued for its role as a bioavailability enhancer, significantly improving the absorption and efficacy of other active ingredients in various formulations. It is primarily sought after by manufacturers in the nutraceutical, cosmeceutical, and pharmaceutical industries for its ability to potentiate the effects of key actives.

Application

• Nutraceutical & Dietary Supplements: As a bioavailability enhancer (bio-enhancer) for vitamins, minerals, herbal extracts, and other poorly absorbed nutrients.
• Pharmaceutical Formulations: To improve the absorption and therapeutic efficacy of certain active pharmaceutical ingredients (APIs), potentially reducing required dosages.
• Cosmetic & Personal Care: Incorporated into topical creams and serums to enhance skin penetration and the effectiveness of anti-aging, brightening, or moisturizing agents.
• Functional Food & Beverages: Used to boost the bioavailability of added nutrients or bioactive compounds in fortified products.
• Veterinary Products: Applied in animal health supplements to improve the uptake of essential nutrients and medications.
• Research & Development: Serves as a key reference standard and investigational compound in pharmacokinetic and formulation studies.

Basic Information

Product Name	Tetrahydropiperine
CAS No.	23434-88-0
Molecular Formula	C17H21NO3
Molecular Weight	287.36 g/mol
Synonyms	1-Piperoylpiperidine (Hydrogenated); Dihydropiperine; Tetrahydro-piperine; Piperine, tetrahydro-; 5-Benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-penta-2,4-dien-1-one (hydrogenated); Bioavailability Enhancer BSE; Piperine Derivative
EINECS	Contact for details

Quality Control

Our Tetrahydropiperine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring GMP, ISO, and other relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.