Description

Ethyl 2,2,2-Trichloroacetimidate is a versatile and highly reactive chemical building block, primarily used as a key reagent in organic synthesis. Its core value lies in its ability to function as an efficient activating agent for the formation of glycosidic bonds, a critical step in carbohydrate and nucleoside chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex molecule synthesis.

Application

• Glycosylation Reactions: A pivotal reagent for the activation of glycosyl donors in the synthesis of oligosaccharides, glycoconjugates, and complex natural products.
• Nucleoside & Nucleotide Synthesis: Used in the preparation of modified nucleosides and nucleotides, which are crucial for antiviral and anticancer drug development.
• Pharmaceutical Intermediates: Serves as a key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Employed in the production of advanced crop protection agents and herbicides that require selective chemical transformations.
• Peptide Chemistry: Can be utilized as a coupling agent or protecting group strategy in the synthesis of specific peptide sequences.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymeric materials with specialized properties.

Basic Information

Product Name	Ethyl 2,2,2-Trichloroacetimidate
CAS No.	23213-96-9
Molecular Formula	C4H6Cl3NO
Molecular Weight	190.45 g/mol
Synonyms	Ethyl Trichloroacetimidate; 2,2,2-Trichloroethyl Acetimidate; Trichloroacetimidic Acid Ethyl Ester; NSC 163049; Ethyl 2,2,2-Trichloroethanimidate; Ethyl Ester of Trichloroacetimidic Acid; O-Ethyl Trichloroacetimidate; Ethyl Trichloroethanimidate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2,2-Trichloroacetimidate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for research and commercial-scale supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.