Description

1-Iodo-2,4,5-Trimethoxybenzene is a high-purity iodinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the construction of complex molecules, particularly in pharmaceutical and materials science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via metal-catalyzed cross-coupling reactions like Suzuki or Stille couplings.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the iodine moiety facilitates further functionalization.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and liquid crystals, due to its electron-rich aromatic system.
• Chemical Synthesis: Employed as a versatile reagent in organic synthesis for introducing the 2,4,5-trimethoxyphenyl group into target molecules.
• Ligand & Catalyst Development: Useful in the preparation of specialized ligands for transition metal catalysis.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory chemistry in research laboratories.

Basic Information

Product Name	1-Iodo-2,4,5-Trimethoxybenzene
CAS No.	23149-33-9
Molecular Formula	C9H11IO3
Molecular Weight	294.09 g/mol
Synonyms	2,4,5-Trimethoxyiodobenzene; 2,4,5-Trimethoxy-1-iodobenzene; 1-Iodo-2,4,5-trimethoxybenzene; Iodo-2,4,5-trimethoxybenzene; Benzene, 1-iodo-2,4,5-trimethoxy-; 23149-33-9
EINECS	Contact for details

Quality Control

Our 1-Iodo-2,4,5-Trimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.