Description

2-(Hydroxymethyl)Cyclobutan-1-One is a versatile and synthetically valuable cyclic ketone bearing a hydroxymethyl functional group. This bifunctional molecule serves as a crucial chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Fine Chemical Building Block: Employed in the preparation of complex natural products, flavors, fragrances, and specialty polymers.
• Material Science Research: Acts as a monomer or precursor for novel biodegradable polymers, resins, and liquid crystals.
• Asymmetric Catalysis: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	2-(Hydroxymethyl)Cyclobutan-1-One
CAS No.	23107-52-0
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	2-(Hydroxymethyl)cyclobutanone; Cyclobutanone, 2-(hydroxymethyl)-; 2-Hydroxymethylcyclobutanone; (Hydroxymethyl)cyclobutanone; 2-Cyclobutanone methanol; 1-Cyclobutanone-2-methanol; α-(Hydroxymethyl)cyclobutanone
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)Cyclobutan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.