Description

(-)-4',5,5'',7''-Tetrahydroxy-4''',7-Dimethoxy-6,8''-Biflavone CAS NO 22969-75-1 is a specialized biflavonoid compound, a dimeric flavonoid characterized by its unique tetrahydroxy-dimethoxy substitution pattern. This compound is valued for its role as a high-purity reference standard and a key bioactive phytochemical in advanced research and development. It is primarily sought by industries focused on pharmaceutical discovery, nutraceutical formulation, and advanced chemical synthesis where precise molecular structure and purity are critical.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity testing, and quantification of biflavonoids in drug discovery and quality control laboratories.
• Bioactive Ingredient Research: Serves as a lead compound or intermediate in the development of therapeutics targeting inflammation, oxidative stress, and metabolic disorders.
• Nutraceutical and Cosmetic Actives: Investigated for incorporation into advanced dietary supplements and cosmeceutical products for its potential antioxidant and skin-protective properties.
• Academic and R&D Studies: A crucial tool for studying the structure-activity relationships (SAR) of biflavonoids and their biochemical pathways.
• Analytical Chemistry: Employed as a calibration standard in chromatographic methods (HPLC, LC-MS) for the analysis of complex plant extracts and biological samples.
• Chemical Synthesis Intermediate: Used as a building block for the semi-synthesis of novel flavonoid derivatives with enhanced biological activity.

Basic Information

Product Name	(-)-4',5,5'',7''-Tetrahydroxy-4''',7-Dimethoxy-6,8''-Biflavone
CAS No.	22969-75-1
Molecular Formula	C32H22O10
Molecular Weight	566.51 g/mol
Synonyms	(-)-Amentoflavone 4''',7-dimethyl ether; 4''',7-Di-O-methylamentoflavone; 6,8''-Biflavone, 4',5,5'',7''-tetrahydroxy-4''',7-dimethoxy-; (2S)-2-[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4-chromenone; Amentoflavone dimethyl ether; Tetrahydroxydimethoxybiflavone
EINECS	Contact for details

Quality Control

Our (-)-4',5,5'',7''-Tetrahydroxy-4''',7-Dimethoxy-6,8''-Biflavone is produced and controlled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure it meets the exacting standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.