Description

Thioacetic Acid S-(Pentafluorophenyl) Ester is a specialized organosulfur and organofluorine reagent featuring a highly reactive thioester linkage to a perfluorinated aromatic ring. This compound matters as a versatile building block for introducing the pentafluorophenylthio moiety, a valuable functional group in advanced material and pharmaceutical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules and modifying surfaces.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing sulfur-containing pharmacophores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the pentafluorophenyl group enhances biological activity and stability.
• Polymer & Material Science: Acts as a monomer or modifying agent for creating specialty polymers, coatings, and advanced materials with unique surface properties.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Useful in modifying biomolecules, peptides, and proteins for research and diagnostic applications.
• Organic Synthesis Reagent: A valuable tool for constructing C-S bonds and performing thioacylation reactions in complex synthetic pathways.

Basic Information

Product Name	Thioacetic Acid S-(Pentafluorophenyl) Ester
CAS No.	22891-72-1
Molecular Formula	C8H3F5OS
Molecular Weight	242.17 g/mol
Synonyms	S-Pentafluorophenyl thioacetate; Pentafluorophenyl thioacetate; Thioacetic acid S-(2,3,4,5,6-pentafluorophenyl) ester; Acetothioic acid S-pentafluorophenyl ester; 2,3,4,5,6-Pentafluorophenyl thioacetate; PFP-thioacetate
EINECS	Contact for details

Quality Control

Our Thioacetic Acid S-(Pentafluorophenyl) Ester is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.