Description

Silybin is a major bioactive flavonolignan and the primary constituent of silymarin, a standardized extract from milk thistle (*Silybum marianum*). This compound is valued for its potent hepatoprotective and antioxidant properties, making it a critical ingredient in advanced nutraceutical and pharmaceutical formulations. It is essential for manufacturers in the dietary supplement, functional food, and pharmaceutical industries seeking high-purity, standardized active ingredients for liver health and detoxification support products.

Application

• Pharmaceutical Intermediates: Used as a key active pharmaceutical ingredient (API) in hepatoprotective and liver support medications.
• Dietary Supplements & Nutraceuticals: A core component of standardized milk thistle extracts for capsules, tablets, and liquid formulations targeting liver health.
• Functional Food & Beverages: Incorporated into health-focused food and drink products designed to support detoxification and antioxidant defense.
• Cosmeceuticals: Utilized in topical skincare formulations for its antioxidant and anti-inflammatory benefits, helping to protect skin from environmental stressors.
• Veterinary Pharmaceuticals: Applied in animal health products for liver support and detoxification in livestock and companion animals.
• Research & Development: Serves as a reference standard and biochemical tool in pharmacological and toxicological studies investigating liver function and oxidative stress.

Basic Information

Product Name	Silybin
CAS No.	22888-70-6
Molecular Formula	C25H22O10
Molecular Weight	482.44 g/mol
Synonyms	Silibinin; Silymarin I; Silybin A/B (mixture); Silibinin A; Silibinin B; 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin; (+)-Silybin; Milk Thistle Extract (primary component)
EINECS	245-302-8

Quality Control

Our Silybin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. It is typically manufactured to meet standards relevant for nutraceutical and pharmaceutical-grade ingredients. Our products undergo rigorous quality testing, including HPLC for assay and impurity profiling, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and safety parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; prolonged exposure to light, air, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (Silybin A+B)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Total Aerobic Microbial Count	≤ 1000 CFU/g
Total Yeast & Mold Count	≤ 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.