Description

(R)-4-Hydroxy-5-Methylfuran-2(5H)-One is a high-purity chiral lactone, a key building block in organic synthesis. Its value lies in its stereochemistry, which is essential for producing optically active compounds with specific biological activities. This product is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), flavors, and fragrances.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Flavor and Fragrance Precursor: Used in the research and development of natural and synthetic flavoring agents, particularly those with lactonic notes.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct stereogenic centers.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and novel chemical entities.
• Agrochemical Development: Potential use as an intermediate in the synthesis of chiral agrochemicals and plant growth regulators.

Basic Information

Product Name	(R)-4-Hydroxy-5-Methylfuran-2(5H)-One
CAS No.	22885-98-9
Molecular Formula	C5H6O3
Molecular Weight	114.10 g/mol
Synonyms	(R)-5-Methyl-4-hydroxy-2(5H)-furanone; (R)-4-Hydroxy-5-methyl-2(5H)-furanone; (R)-Pantolactone; (R)-Pantoyl lactone; (R)-D-Pantolactone; (R)-2-Hydroxy-3,3-dimethyl-γ-butyrolactone; (R)-3-Hydroxy-4,4-dimethyl-dihydrofuran-2(3H)-one
EINECS	245-293-4

Quality Control

Our (R)-4-Hydroxy-5-Methylfuran-2(5H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	90 - 94 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.