Description

Cyclopropanecarboxylic Acid, 2-Nitro-, cis- (8Ci) is a specialized nitro-substituted cyclopropane derivative, a high-value chiral building block in advanced organic synthesis. Its unique strained-ring structure and functional groups make it a critical intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. CAS number 22882-44-6.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in areas requiring stereochemical control.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of novel polymers and functional materials with unique properties derived from the strained ring system.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cycloaddition and ring-opening reactions.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Nitro-, cis- (8Ci)
CAS No.	22882-44-6
Molecular Formula	C4H5NO4
Molecular Weight	131.09 g/mol
Synonyms	cis-2-Nitrocyclopropanecarboxylic Acid; (1R,2S)-rel-2-Nitrocyclopropanecarboxylic Acid; 2-Nitrocyclopropanecarboxylic acid, cis-; NSC 163082; (1S,2R)-2-Nitrocyclopropane-1-carboxylic Acid; Cyclopropanecarboxylic acid, 2-nitro-, (1R,2S)-rel-; (±)-cis-2-Nitrocyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of Cyclopropanecarboxylic Acid, 2-Nitro-, cis- is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (by HPLC), enantiomeric excess, and impurity profiles. Our quality system is designed to meet the exacting standards of GMP and ISO-guided environments for research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% cis-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.