Description

4-tert-Butylphenyl Chlorothionoformate is a specialized organosulfur reagent used as a key building block in advanced organic synthesis. This compound matters for its role in introducing the thiocarbonyl functional group, enabling the synthesis of complex molecules with high precision and efficiency. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those requiring thiocarbamate or dithiocarbonate moieties.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides where the thiocarbonyl group enhances biological activity.
• Polymer Chemistry: Acts as a modifying agent or chain transfer agent in the production of specialty polymers with tailored properties.
• Material Science Research: Employed in surface modification and the creation of functional materials with specific chemical receptors.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Organic Synthesis Reagent: A versatile reagent for constructing C-S bonds and synthesizing heterocyclic compounds in academic and industrial R&D.

Basic Information

Product Name	4-tert-Butylphenyl Chlorothionoformate
CAS No.	22857-48-3
Molecular Formula	C11H13ClOS
Molecular Weight	228.74 g/mol
Synonyms	p-tert-Butylphenyl Chlorothionoformate; 4-(1,1-Dimethylethyl)phenyl Chlorothionoformate; Chlorothionoformic Acid 4-tert-Butylphenyl Ester; 1-Chloro-1-thioformyloxy-4-tert-butylbenzene; 4-tert-Butyl Phenyl Chlorothionoformate; 4-tert-Butylphenoxythiocarbonyl Chloride; p-tert-Butylphenoxythiocarbonyl Chloride; Thiocarbonyl Chloride O-(4-tert-Butylphenyl) Ester
EINECS	Contact for details

Quality Control

Our 4-tert-Butylphenyl Chlorothionoformate is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. Each lot undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.