Description

1,2-Di-o-Acetyl-3,5-Di-o-Benzoyl-3-β-C-Methyl-D-Ribofuranose is a key protected ribofuranose derivative, a crucial chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex nucleoside analogs and other biologically active molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of modified nucleosides and nucleotides for antiviral and anticancer drug candidates.
• Antiviral Drug Development: Used in the research and production of novel nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral agents.
• Biochemical Research: Serves as a specialized substrate or building block for studying enzyme mechanisms and metabolic pathways involving sugar nucleotides.
• Carbohydrate Chemistry: A valuable starting material for the synthesis of complex, selectively protected sugars and glycomimetics.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis projects for clients in the life sciences industry.

Basic Information

Product Name	1,2-Di-o-Acetyl-3,5-Di-o-Benzoyl-3-β-C-Methyl-D-Ribofuranose
CAS No.	22672-43-1
Molecular Formula	C24H24O9
Molecular Weight	456.44 g/mol
Synonyms	3-C-Methyl-1,2-di-O-acetyl-3,5-di-O-benzoyl-D-ribofuranose; 1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-C-methyl-D-ribofuranose; 3-C-Methyl-1,2-di-O-acetyl-3,5-di-O-benzoyl-α/β-D-ribofuranose; 3-C-Methyl-D-ribofuranose 1,2-diacetate 3,5-dibenzoate; Protected 3-C-Methyl-D-ribofuranose; 3-C-Methyl-ribofuranose derivative
EINECS	Contact for details

Quality Control

Our 1,2-Di-o-Acetyl-3,5-Di-o-Benzoyl-3-β-C-Methyl-D-Ribofuranose is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.