Description

4-Bromo-3(2H)-Pyridazinone is a versatile brominated heterocyclic building block of significant importance in modern synthetic organic chemistry. Its core value lies in its reactivity as a key intermediate for constructing more complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by research chemists and process development scientists working on the synthesis of novel active pharmaceutical ingredients (APIs), crop protection agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyridazinone scaffold's bioactivity.
• Chemical Research & Development: Acts as a versatile building block for creating novel heterocyclic compounds in academic and industrial R&D settings.
• Material Science: Potential intermediate in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Library Synthesis: Employed in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-Bromo-3(2H)-Pyridazinone
CAS No.	22626-56-8
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	4-Bromo-3(2H)-pyridazinone; 4-Bromo-2H-pyridazin-3-one; 4-Bromo-3-pyridazinol; 4-Bromo-3-hydroxypyridazine; 3-Hydroxy-4-bromopyridazine; 4-Bromopyridazin-3-ol; 22626-56-8; 4-Bromo-3-pyridazinone
EINECS	Contact for details

Quality Control

Our 4-Bromo-3(2H)-Pyridazinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.