Description

(+)-Cyclosativene CAS NO 22469-52-9 is a high-purity, naturally occurring sesquiterpene enantiomer valued for its unique and complex bicyclic structure. This compound is of significant interest in advanced fragrance and flavor creation, where its specific stereochemistry imparts distinct olfactory characteristics not found in its racemic or opposite enantiomer forms. It serves as a critical chiral building block and reference standard for research and development in the fine chemical, aroma chemical, and pharmaceutical sectors, enabling the synthesis of novel compounds and the study of stereospecific biological activity.

Application

• Fragrance & Flavor Industry: A key chiral ingredient for creating sophisticated, high-value perfumes and flavor compositions, where its specific enantiomeric form is essential for the desired scent profile.
• Aroma Chemical Synthesis: Used as a premium chiral intermediate in the synthesis of complex terpenoid-based aroma molecules.
• Pharmaceutical Research: Employed as a chiral starting material or reference standard in medicinal chemistry for developing new active pharmaceutical ingredients (APIs).
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) in quality control and research laboratories.
• Academic & Industrial R&D: Utilized in chemical research to study terpene biosynthesis, catalysis, and the effects of stereochemistry on material properties.
• Fine Chemical Manufacturing: Acts as a specialized intermediate for producing other high-value, optically active chemical products.

Basic Information

Product Name	(+)-Cyclosativene
CAS No.	22469-52-9
Molecular Formula	C15H24
Molecular Weight	204.35 g/mol
Synonyms	(+)-Cyclosativene; (1R,7S,8S)-4,4,8-Trimethyltricyclo[6.3.0.0¹,⁷]undecane; Cyclosativene; (1R,7S,8S)-4,4,8-Trimethyltricyclo[6.3.0.0¹,⁷]undec-2-ene; NSC 221927; (+)-1(10),4-Cadinadiene
EINECS	Contact for details

Quality Control

Our (+)-Cyclosativene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is rigorously analyzed using advanced chromatographic and spectroscopic techniques, including chiral GC and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment, supporting compliance in GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (GC-MS)	Conforms to reference standard
Purity (GC)	≥ 95.0%
Enantiomeric Purity (Chiral GC)	≥ 98.0% ee
Refractive Index (n20D)	1.495 - 1.505
Specific Rotation ([α]20D)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.