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Calcium Orotate CAS NO 22454-86-0
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CAS No.:22454-86-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Calcium Orotate is a mineral salt complex of calcium and orotic acid, a compound naturally involved in the biosynthesis of pyrimidines. This specialized form is valued for its potential role in supporting cellular energy metabolism and mineral utilization. It is primarily utilized in the formulation of high-end dietary supplements and nutraceuticals, targeting markets that demand bioavailable and synergistic mineral ingredients.
Application
- Dietary Supplements & Nutraceuticals: A key ingredient in formulations designed to support bone health, cardiovascular function, and cellular energy production.
- Sports Nutrition: Incorporated into products aimed at enhancing mineral retention, recovery, and athletic performance.
- Functional Food & Beverage Fortification: Used to enrich health-focused foods and drinks with bioavailable calcium.
- Pharmaceutical Intermediates: Serves as a precursor or active component in the development of specialized medicinal products.
- Veterinary Nutrition: Applied in premium animal feed and supplement formulas for livestock and companion animals.
- Cosmeceutical Preparations: Used in topical formulations for skin health due to calcium's role in skin barrier function.
Basic Information
| Product Name | Calcium Orotate |
| CAS No. | 22454-86-0 |
| Molecular Formula | C10H12CaN4O8 • xH2O |
| Molecular Weight | Anhydrous: 356.31 g/mol |
| Synonyms | Calcium Orotate; Calcium Orotate Hydrate; Calcium Orotat; Orotic Acid Calcium Salt; Calcium 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylate; Calcium Diorotate; Calcium Orotate Complex; Calcium Orotat Hydrate |
| EINECS | Contact for details |
Quality Control
Our Calcium Orotate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, ensuring compliance with relevant standards for nutraceutical and pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to standard |
| Assay (Calcium Orotate) | ≥ 98.0% |
| Loss on Drying | ≤ 2.0% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Arsenic (As) | ≤ 2 ppm |
| Residual Solvents | Complies with ICH guidelines |
| Microbiological Analysis | Total Plate Count: ≤ 1000 cfu/g; Yeast & Mold: ≤ 100 cfu/g; Absence of E. coli, Salmonella |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






