Description

4,6-Dibromo-2,3-Dimethylaniline is a halogenated aniline derivative serving as a versatile and critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of bromine atoms and methyl groups on the aromatic ring, which facilitates selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the dibromo-aniline core contributes to biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and high-performance pigments, providing enhanced color fastness and thermal stability.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers requiring specific brominated aromatic units.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination, enabling carbon-carbon and carbon-nitrogen bond formation.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	4,6-Dibromo-2,3-Dimethylaniline
CAS No.	22364-27-8
Molecular Formula	C8H9Br2N
Molecular Weight	278.97 g/mol
Synonyms	2,3-Dimethyl-4,6-dibromoaniline; 4,6-Dibromo-2,3-dimethylbenzenamine; 2,3-Dimethyl-4,6-dibromobenzenamine; 4,6-Dibromo-o-xylidine; Aniline, 4,6-dibromo-2,3-dimethyl-; 2,3-Dimethyl-4,6-dibromo aniline; 4,6-Dibromo-2,3-dimethyl-phenylamine
EINECS	Contact for details

Quality Control

Our 4,6-Dibromo-2,3-Dimethylaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.