Description

Benzenesulfonyl-Difluoro-Acetic Acid Methyl Ester is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a benzenesulfonyl and a difluoroacetate moiety, makes it a versatile precursor for introducing fluorinated motifs into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to incorporate the difluoroacetate ester group into complex organic frameworks.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for studying biological mechanisms and enzyme activity.

Basic Information

Product Name	Benzenesulfonyl-Difluoro-Acetic Acid Methyl Ester
CAS No.	22340-47-2
Molecular Formula	C9H8F2O4S
Molecular Weight	250.22 g/mol
Synonyms	Methyl 2-(Benzenesulfonyl)-2,2-difluoroacetate; Methyl Benzenesulfonyldifluoroacetate; 2,2-Difluoro-2-(phenylsulfonyl)acetic Acid Methyl Ester; α,α-Difluoro-α-(phenylsulfonyl)acetic Acid Methyl Ester; Difluoro(phenylsulfonyl)acetic Acid Methyl Ester; Methyl α,α-Difluoro-α-(phenylsulfonyl)acetate; (Phenylsulfonyl)difluoroacetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl-Difluoro-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.