Description

2,2-Dimethylpropane-1,3-Diyl Bis(4-Methylbenzenesulfonate) is a high-purity chemical intermediate featuring a neopentyl core with dual tosylate leaving groups. This compound matters for its role as a versatile building block in organic synthesis, enabling the controlled introduction of the neopentyl moiety into target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring rigid, bulky neopentyl structures to modulate biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the neopentyl group can enhance lipophilicity and environmental persistence.
• Polymer Chemistry: Serves as a cross-linking agent or monomer precursor for the development of specialty polymers with unique thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated phosphine or nitrogen-based ligands for asymmetric catalysis and material science applications.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for nucleophilic substitution reactions (SN2) due to the excellent leaving group ability of the tosylate esters.
• Material Science: Potential use in the surface functionalization of nanoparticles and the creation of advanced organic frameworks.

Basic Information

Product Name	2,2-Dimethylpropane-1,3-Diyl Bis(4-Methylbenzenesulfonate)
CAS No.	22308-12-9
Molecular Formula	C21H26O6S2
Molecular Weight	438.56 g/mol
Synonyms	Neopentyl Glycol Ditosylate; 2,2-Bis[(4-methylphenyl)sulfonyloxymethyl]propane; 1,3-Bis(p-toluenesulfonyloxy)-2,2-dimethylpropane; 2,2-Dimethyl-1,3-propanediol Ditosylate; Neopentanediol Ditosylate; Pentaerythritol Ditosylate Derivative; Ditosylneopentyl Glycol; NSC 3340
EINECS	Contact for details

Quality Control

Our 2,2-Dimethylpropane-1,3-Diyl Bis(4-Methylbenzenesulfonate) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.