Description

Rel-(1R,3S)-3-Hydroxycyclohexanecarboxylic Acid is a high-purity chiral building block of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry, which is critical for imparting specific biological activity and physical properties in final products. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where stereochemistry affects efficacy and environmental profile.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Fine Chemical and Flavor/Fragrance Ingredient: Employed in the synthesis of high-value specialty chemicals, including chiral flavors, fragrances, and functional materials.
• Academic and R&D Laboratories: Utilized as a standard or building block in methodological development and synthetic chemistry research.

Basic Information

Product Name	Rel-(1R,3S)-3-Hydroxycyclohexanecarboxylic Acid
CAS No.	22267-35-2
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(1R,3S)-3-Hydroxycyclohexanecarboxylic Acid; trans-3-Hydroxycyclohexanecarboxylic Acid; 3-Hydroxycyclohexanecarboxylic Acid (trans-); rel-(1R,3S)-3-Hydroxy-1-cyclohexanecarboxylic Acid; Cyclohexanecarboxylic acid, 3-hydroxy-, (1R,3S)-rel-; 3-Hydroxycyclohexane-1-carboxylic Acid; NSC 403697
EINECS	Contact for details

Quality Control

Our Rel-(1R,3S)-3-Hydroxycyclohexanecarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.