Description

2-(Benzenesulfonyloxy)-2-Phenyl-Acetonitrile is a specialized organic intermediate featuring a benzenesulfonyloxy leaving group adjacent to a nitrile functionality. This compound matters for its role as a key synthon in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially those containing nitrile or α-substituted phenylacetic acid derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive benzenesulfonate ester group.
• Fine Chemical Production: Serves as a versatile electrophile in nucleophilic substitution reactions for creating specialty chemicals and functional materials.
• Organic Synthesis Research: Employed in academic and industrial laboratories for methodological studies, including C-C and C-O bond-forming reactions.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel chiral or functionalized ligands used in asymmetric catalysis.
• Polymer Modification: Potential use as a monomer or grafting agent in the development of specialty polymers with specific functional groups.

Basic Information

Item	Details
Product Name	2-(Benzenesulfonyloxy)-2-Phenyl-Acetonitrile
CAS No.	22259-85-4
Molecular Formula	C14H11NO3S
Molecular Weight	273.31 g/mol
Synonyms	α-(Benzenesulfonyloxy)benzeneacetonitrile; (Benzenesulfonyloxy)(phenyl)acetonitrile; 2-Phenyl-2-[(phenylsulfonyl)oxy]acetonitrile; Phenyl(benzenesulfonyloxy)acetonitrile; Benzeneacetonitrile, α-(benzenesulfonyloxy)-; O-(Benzenesulfonyl)mandelonitrile; 22259-85-4
EINECS	Contact for details

Quality Control

Our 2-(Benzenesulfonyloxy)-2-Phenyl-Acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.