Description

(2R)-2,3,4Aβ,11Bβ-Tetrahydro-2-(1-Methylethenyl)[1,3]Dioxolo[6,7][1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-12(5H)-One is a complex, high-purity organic compound belonging to the benzopyran-furobenzopyran class, characterized by its specific stereochemistry. This compound matters as a sophisticated chemical intermediate and reference standard, offering precise structural integrity for advanced research and development. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs), natural product derivatives, and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents and complex natural product analogs.
• Reference Standard: Used as a high-purity analytical standard in method development and quality control for chromatographic analysis (HPLC, LC-MS).
• Academic & Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the exploration of new chemical entities with potential biological activity.
• Process Chemistry Development: Acts as a critical intermediate for scaling up synthetic routes in pilot plants and optimizing manufacturing processes.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex natural products containing fused benzopyran and furobenzopyran ring systems.

Basic Information

Product Name	(2R)-2,3,4Aβ,11Bβ-Tetrahydro-2-(1-Methylethenyl)[1,3]Dioxolo[6,7][1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-12(5H)-One
CAS No.	22256-05-9
Molecular Formula	C24H22O7
Molecular Weight	422.43 g/mol
Synonyms	(2R)-2,3,4aβ,11bβ-Tetrahydro-2-isopropenyl-1,3-dioxolo[6,7]-8,9-dimethoxyfuro[3',2':5,6]benzopyrano[4,3-b]benzopyran-12(5H)-one; (2R)-2,3,4aβ,11bβ-Tetrahydro-2-(1-methylethenyl)-1,3-dioxolo[6,7]benzofuro[3',2':5,6]benzopyrano[4,3-b]benzopyran-12(5H)-one; Rotenonone; 12a-Hydroxyrotenone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2R)-2,3,4Aβ,11Bβ-Tetrahydro-2-(1-Methylethenyl)[1,3]Dioxolo[6,7][1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-12(5H)-One is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.