Description

Loganic Acid is a naturally occurring iridoid glycoside, a key intermediate in the biosynthetic pathway of secoiridoids and other bioactive compounds. Its significance lies in its role as a versatile building block for pharmaceutical research and a marker for quality control in herbal extracts. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and botanical extract industries seeking to develop or standardize products based on traditional medicinal plants.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of more complex secoiridoids and indole alkaloids with potential therapeutic activities.
• Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of loganic acid in herbal materials and finished products via HPLC or LC-MS.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into standardized botanical extracts, particularly those derived from *Gentiana lutea* (Gentian) and *Olea europaea* (Olive leaf), to ensure potency and consistency.
• Biochemical Research: Employed in studies investigating the biosynthesis, metabolism, and biological activities of iridoid compounds.
• Cosmeceutical Ingredients: Explored for potential antioxidant and anti-inflammatory properties in advanced skincare formulations.
• Quality Control & Assurance: Essential for analytical laboratories performing assay and purity tests for raw materials and herbal medicinal products.

Basic Information

Product Name	Loganic Acid
CAS No.	22255-40-9
Molecular Formula	C16H24O10
Molecular Weight	376.36 g/mol
Synonyms	Loganic acid; (1S,4aS,7S,7aR)-1-((β-D-Glucopyranosyl)oxy)-1,4a,5,6,7,7a-hexahydro-7-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid; 7-Epiloganic acid; Loganate; Loniceroside; Epiloganic acid; Gentianine precursor
EINECS	244-879-9

Quality Control

Our Loganic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and manufacturing. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with in-house specifications tailored for use as a pharmaceutical intermediate or analytical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.