Description

2-Oleoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine (PC) with an oleoyl fatty acid chain at the sn-1 position. This compound is a critical building block for creating advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries who require precise, well-defined lipids for formulation development and fundamental studies of membrane biology.

Application

• Liposome & Nanoparticle Formulation: A key component for constructing stable, uniform liposomes and lipid nanoparticles (LNPs) used in drug and gene delivery.
• Biomembrane Research: Used to create model cell membranes (e.g., supported lipid bilayers, vesicles) for studying protein-lipid interactions, membrane permeability, and cellular processes.
• Pharmaceutical Excipient: Serves as a solubilizing agent and bioavailability enhancer in injectable and oral formulations.
• Diagnostic Reagents: Incorporated into assay kits and diagnostic tools that rely on membrane-based recognition events.
• Cosmetic Formulations: Used in high-end skincare products for its emollient properties and ability to form lamellar structures that support skin barrier function.
• Cell Culture & Cryopreservation: Acts as a protective agent in media supplements and cryoprotectant solutions for maintaining cell viability.

Basic Information

Product Name	2-Oleoyl-Sn-Glycero-3-Phosphocholine
CAS No.	22248-65-3
Molecular Formula	C44H86NO8P
Molecular Weight	788.13 g/mol
Synonyms	1-Oleoyl-2-hydroxy-sn-glycero-3-phosphocholine; POPC (common abbreviation for 1-palmitoyl-2-oleoyl-phosphatidylcholine - note: this is a related but distinct compound); 18:1 PC (Oleoyl); (2R)-2-Hydroxy-3-(trimethylammonio)propyl (9Z)-octadec-9-enoate hydrogen phosphate; 3-sn-Phosphatidylcholine, 1-oleoyl-2-hydroxy-; Lyso-oleoyl phosphatidylcholine; LPC(18:1); Oleoyl lysophosphatidylcholine
EINECS	Contact for details

Quality Control

Our 2-Oleoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for research and GMP-grade applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, LC-MS) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate. The product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Peroxide Value	≤ 3.0 mEq/kg
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.