Description

2-Hydroxy-2-(Thiophen-3-Yl)Acetic Acid is a versatile chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in the presence of both a carboxylic acid and a secondary alcohol functional group attached to a thiophene heterocycle, enabling its use in constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the preparation of advanced crop protection agents and herbicides, leveraging the bioactivity of the thiophene moiety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Material Science Research: Investigated as a monomer or functional additive for creating novel polymers with specific electronic or optical properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in organic synthesis and heterocyclic chemistry.
• Fine Chemical Production: Acts as a building block for the synthesis of specialty chemicals and complex organic molecules.

Basic Information

Product Name	2-Hydroxy-2-(Thiophen-3-Yl)Acetic Acid
CAS No.	22098-20-0
Molecular Formula	C6H6O3S
Molecular Weight	158.18 g/mol
Synonyms	3-Thienylglycolic Acid; 2-Hydroxy-2-(3-thienyl)acetic Acid; α-Hydroxy-3-thiopheneacetic Acid; (3-Thienyl)hydroxyacetic Acid; 2-(3-Thienyl)-2-hydroxyacetic Acid; 2-Hydroxy-2-(thiophen-3-yl)ethanoic Acid; (±)-2-Hydroxy-2-(thiophen-3-yl)acetic Acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-(Thiophen-3-Yl)Acetic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.