Description

n-Hydroxyacetamidine is a versatile amidine derivative serving as a key synthetic intermediate in organic chemistry. Its primary value lies in its bifunctional reactivity, acting as a precursor for heterocyclic compounds and a building block for pharmaceuticals and agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various nitrogen-containing heterocycles, such as imidazoles and pyrimidines, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its amidine functionality contributes to the biological activity of the final product.
• Fine Chemical Production: Serves as a specialized reagent for the synthesis of dyes, pigments, and complex organic molecules requiring specific amidine linkages.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways involving C-N bond formation.
• Coordination Chemistry: Can act as a ligand or precursor for ligands in metal-organic frameworks (MOFs) and catalytic complexes due to its nitrogen donor atoms.

Basic Information

Product Name	n-Hydroxyacetamidine
CAS No.	22059-22-9
Molecular Formula	C2H6N2O
Molecular Weight	74.08 g/mol
Synonyms	Acetamidoxime; N-Hydroxyethanimidamide; Acetamidine, N-hydroxy-; Acetamidoxime; Ethanamidoxime; Acetimidic acid, amidoxime; 1-Amino-1-hydroxyiminoethane; Acetohydroxamic acid amidine
EINECS	244-746-7

Quality Control

Our n-Hydroxyacetamidine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including identification by FT-IR, purity assessment by HPLC, and residual solvent analysis by GC, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent decomposition. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.