Description

3-[3,4-Bis(Trimethylsilyloxy)Phenyl]Propenoic Acid Methyl Ester is a high-value organosilicon intermediate featuring a protected catechol moiety and an α,β-unsaturated ester functional group. This unique structure makes it a critical building block for synthesizing complex molecules in advanced pharmaceutical and material science research. It is primarily sought after by R&D chemists and process development scientists working in fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Organic Synthesis Building Block: Used in cross-coupling reactions, Michael additions, and as a precursor for more complex silicon-containing compounds.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and silicon-based hybrid materials.
• Agrochemical Synthesis: Intermediate in the research and development of new active ingredients with enhanced properties.
• Liquid Crystal & OLED Material Development: Utilized in the synthesis of advanced organic electronic materials due to its stable silyl ether groups and conjugated system.

Basic Information

Product Name	3-[3,4-Bis(Trimethylsilyloxy)Phenyl]Propenoic Acid Methyl Ester
CAS No.	22020-29-7
Molecular Formula	C16H26O4Si2
Molecular Weight	338.55 g/mol
Synonyms	Methyl 3-[3,4-Bis(trimethylsilyloxy)phenyl]acrylate; Methyl 3-(3,4-Bis((trimethylsilyl)oxy)phenyl)-2-propenoate; 3,4-Bis(trimethylsiloxy)cinnamic acid methyl ester; TMS-protected methyl caffeate derivative; 22020-29-7; Methyl 3-(3,4-dihydroxyphenyl)acrylate bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our production of 3-[3,4-Bis(Trimethylsilyloxy)Phenyl]Propenoic Acid Methyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized by GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.