Description

2-Benzyloxy-Acetamidine Hcl is a high-purity organic chemical building block characterized by its amidine functional group protected with a benzyloxy moiety. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive amidine group.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein function.
• Peptidomimetic Chemistry: Integral for the design and synthesis of peptide analogs and mimetics with enhanced stability or activity.
• Heterocyclic Compound Synthesis: Employed in the construction of various nitrogen-containing heterocycles, which are common scaffolds in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	2-Benzyloxy-Acetamidine Hcl
CAS No.	22018-43-5
Molecular Formula	C9H13ClN2O
Molecular Weight	200.66 g/mol
Synonyms	2-(Benzyloxy)acetamidine hydrochloride; N-(Benzyloxy)acetamidine hydrochloride; Acetamidine, 2-(phenylmethoxy)-, hydrochloride; 2-Benzyloxyethanimidamide hydrochloride; (Benzyloxy)acetamidine HCl; α-(Benzyloxy)acetamidine hydrochloride; 22018-43-5; BRN 3910377
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-Acetamidine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.