Description

4-Nitro-3-(Trifluoromethyl)Benzenesulphonamide is a specialized aromatic sulfonamide derivative characterized by its nitro and trifluoromethyl substituents, which confer unique reactivity and physicochemical properties. This compound serves as a critical high-value intermediate in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where its distinct molecular framework is utilized to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the bioactivity of the sulfonamide group.
• Chemical Research: Valuable reagent in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Dye and Pigment Industry: Intermediate for the manufacture of specialized dyes and pigments, where the nitro and trifluoromethyl groups influence color and stability.
• Material Science: Potential monomer or additive in the synthesis of high-performance polymers and advanced materials.

Basic Information

Product Name	4-Nitro-3-(Trifluoromethyl)Benzenesulphonamide
CAS No.	21988-05-6
Molecular Formula	C7H5F3N2O4S
Molecular Weight	270.19 g/mol
Synonyms	4-Nitro-3-(trifluoromethyl)benzenesulfonamide; 3-Trifluoromethyl-4-nitrobenzenesulfonamide; Benzenesulfonamide, 4-nitro-3-(trifluoromethyl)-; 4-Nitro-alpha,alpha,α-trifluoro-m-toluenesulfonamide; NSC 163063; 21988-05-6; 4-Nitro-3-trifluoromethylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-Nitro-3-(Trifluoromethyl)Benzenesulphonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.