Description

2-Trimethylsilyloxyhexadecanoic Acid Methyl Ester is a high-value organosilicon-protected fatty acid derivative, serving as a critical synthetic intermediate. Its primary value lies in providing a protected hydroxyl group on a long aliphatic chain, enabling selective chemical transformations in complex organic syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those with long-chain lipid moieties or prodrugs requiring hydroxyl protection.
• Agrochemical Synthesis: Used in the production of specialized surfactants, adjuvants, and active ingredients where a protected fatty acid derivative is needed.
• Lipid Chemistry Research: A valuable reagent for studying lipid metabolism, membrane biophysics, and the synthesis of labeled or modified fatty acids.
• Polymer & Material Science: Serves as a monomer or modifier in creating specialized polymers, coatings, and silicone-organic hybrid materials with unique surface properties.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of high-value, long-chain ester compounds used in specialty formulations.
• Organic Synthesis Reagent: Employed in multi-step syntheses where the trimethylsilyl (TMS) protecting group is required for the selective functionalization of molecules.

Basic Information

Product Name	2-Trimethylsilyloxyhexadecanoic Acid Methyl Ester
CAS No.	21987-11-1
Molecular Formula	C₂₀H₄₂O₃Si
Molecular Weight	358.64 g/mol
Synonyms	Methyl 2-(Trimethylsilyloxy)hexadecanoate; Methyl 2-[(Trimethylsilyl)oxy]palmitate; Hexadecanoic acid, 2-(trimethylsilyloxy)-, methyl ester; 2-TMS-Hexadecanoic Acid Methyl Ester; Methyl 2-TMS-oxyhexadecanoate; Palmitic acid, 2-hydroxy-, methyl ester, 2-(trimethylsilyl) ether; Methyl α-(Trimethylsiloxy)palmitate
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilyloxyhexadecanoic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS and NMR for structural confirmation, to ensure it meets the stringent requirements of research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.