Description

(1S,3Aα)-Octahydro-1,7Aα-Dimethyl-5α-Isopropyl-1,4β-Methano-1H-Inden-8-One is a high-purity, synthetically derived ketone with a complex, rigid polycyclic structure. This compound matters as a versatile and valuable chiral intermediate in advanced organic synthesis, offering a unique steric and electronic profile for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fragrance industries for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel therapeutic agents, particularly in steroid-like or terpenoid-based drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structural complexity can contribute to specific biological activity.
• Fragrance & Flavor Chemistry: Acts as a precursor for high-value aroma chemicals and fixatives, leveraging its stable, camphoraceous backbone.
• Organic Synthesis Research: Employed in academic and industrial laboratories for methodological studies, including catalysis, asymmetric synthesis, and natural product total synthesis.
• Material Science Precursor: Potential use in the development of specialty polymers or liquid crystals due to its rigid, functionalized core structure.

Basic Information

Item	Detail
Product Name	(1S,3Aα)-Octahydro-1,7Aα-Dimethyl-5α-Isopropyl-1,4β-Methano-1H-Inden-8-One
CAS No.	21966-94-9
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	1,4-Methano-1H-inden-8-one, octahydro-1,7a-dimethyl-5-(1-methylethyl)-, (1S,3aS,5aR,7aS,7bR)-; (-)-α-Santonin; Santonin; (1S,3aS,5aR,7aS,7bR)-Octahydro-1,7a-dimethyl-5-(1-methylethyl)-1,4-methano-1H-inden-8-one; L-Santonin; Levosantonin; α-Santonin; Santonine
EINECS	244-663-6

Quality Control

Every batch of our (1S,3Aα)-Octahydro-1,7Aα-Dimethyl-5α-Isopropyl-1,4β-Methano-1H-Inden-8-One is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-170° to -178° (c=1 in CHCl3)
Melting Point	171°C - 175°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.