Description

(R)-7-Hydroxy-8,8-Dimethyl-7,8-Dihydro-2H,6H-Benzo[1,2-B:5,4-B']Dipyran-2-One is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, optically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides.
• Asymmetric Synthesis: Serves as a valuable building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity.
• Academic & Industrial R&D: A key reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-7-Hydroxy-8,8-Dimethyl-7,8-Dihydro-2H,6H-Benzo[1,2-B:5,4-B']Dipyran-2-One
CAS No.	21860-31-1
Molecular Formula	C₁₄H₁₄O₄
Molecular Weight	246.26 g/mol
Synonyms	(R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-chromeno[5,4-c]chromen-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-chromeno[5,4-c]chromene-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one; (R)-7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one
EINECS	Contact for details

Quality Control

Our (R)-7-Hydroxy-8,8-Dimethyl-7,8-Dihydro-2H,6H-Benzo[1,2-B:5,4-B']Dipyran-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and chiral analysis, to meet the stringent requirements of pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, well-ventilated area. Due to its light-sensitive and easily oxidized nature, prolonged exposure to light, air, or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.