Description

3-Cyclobutylpropan-1-ol is a valuable aliphatic alcohol building block featuring a cyclobutyl substituent, offering a unique combination of rigidity and reactivity for advanced chemical synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and specialty materials industries seeking to introduce the compact, strained cyclobutane ring system into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the cyclobutyl moiety can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Potential building block for synthesizing unique musk and woody odorants due to its specific hydrocarbon skeleton.
• Material Science Monomer: Can be utilized to create specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in various carbon-carbon bond forming reactions, including alkylations and cross-coupling reactions.

Basic Information

Product Name	3-Cyclobutylpropan-1-ol
CAS No.	21782-48-9
Molecular Formula	C7H14O
Molecular Weight	114.19 g/mol
Synonyms	3-Cyclobutyl-1-propanol; Cyclobutylpropanol; 3-Cyclobutylpropyl alcohol; 1-Propanol, 3-cyclobutyl-; (3-Cyclobutylpropyl) alcohol; NSC 169045; 3-Cyclobutylpropanol
EINECS	Contact for details

Quality Control

Our 3-Cyclobutylpropan-1-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (IR, NMR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Density (g/mL, 20°C)	0.910 - 0.930

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.