Description

Benzoic Acid, 4-Chloro-, (1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl Ester is a high-purity, optically active ester derivative of chlorobenzoic acid and menthol, identified by CAS number 21758-34-9. This specialty chemical is valued for its unique stereochemistry and functional groups, making it a critical chiral intermediate and building block in advanced synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or requiring specific stereochemical configurations.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides and herbicides where the specific spatial orientation of the molecule influences biological activity and selectivity.
• Fine Chemical Production: Acts as a precursor in the synthesis of complex fragrances, flavors, and other high-value specialty chemicals that benefit from its defined stereochemistry.
• Academic & Industrial Research: Employed in chemical research as a standard or reagent for studying esterification reactions, chiral resolution, and asymmetric synthesis methodologies.
• Liquid Crystal & Advanced Material Precursor: Potential use in the synthesis of organic components for liquid crystal displays (LCDs) and other advanced organic materials due to its rigid, substituted aromatic and alicyclic structure.

Basic Information

Product Name	Benzoic Acid, 4-Chloro-, (1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl Ester
CAS No.	21758-34-9
Molecular Formula	C17H23ClO2
Molecular Weight	294.82 g/mol
Synonyms	(-)-Menthyl 4-Chlorobenzoate; L-Menthyl 4-Chlorobenzoate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 4-chlorobenzoate; 4-Chlorobenzoic Acid (1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl Ester; p-Chlorobenzoic Acid Menthyl Ester; (-)-Menthyl p-Chlorobenzoate; 21758-34-9; 4-Chlorobenzoic Acid Menthyl Ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Chloro-, (1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, correct stereochemical configuration, and consistent performance. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are provided and available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.