Description

(R)-(+)-n-(1-Phenylethyl)Phthalamic Acid is a high-purity chiral intermediate of significant importance in asymmetric synthesis and pharmaceutical development. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, which is critical for the efficacy and safety of active pharmaceutical ingredients. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in the production of enantiomerically pure compounds.

Application

• Chiral Auxiliary and Resolving Agent: Widely used for the optical resolution of racemic mixtures of amines, alcohols, and other chiral compounds.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis Catalyst Ligand: Employed in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, such as hydrogenation and alkylation.
• Fine Chemical Synthesis: Used in the research and development of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic and Industrial Research: A valuable tool for methodological development in organic chemistry and process chemistry within R&D laboratories.

Basic Information

Product Name	(R)-(+)-n-(1-Phenylethyl)Phthalamic Acid
CAS No.	21752-35-2
Molecular Formula	C16H15NO3
Molecular Weight	269.30 g/mol
Synonyms	(R)-(+)-N-(1-Phenylethyl)phthalamic Acid; (R)-N-(1-Phenylethyl)phthalmic Acid; (R)-(+)-1-Phenylethylammonium Phthalate; (R)-α-Methylbenzylammonium Phthalate; (R)-PEA Phthalamate; (R)-N-(α-Methylbenzyl)phthalamic Acid; (R)-1-Phenylethylamine Phthalamic Acid Salt; (R)-N-(1-Phenylethyl)phthalamate
EINECS	Contact for details

Quality Control

Our (R)-(+)-n-(1-Phenylethyl)Phthalamic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.